{"id":1006,"date":"2012-02-10T07:46:50","date_gmt":"2012-02-10T07:46:50","guid":{"rendered":"http:\/\/personalpolishing.wordpress.com\/?p=1006"},"modified":"2012-02-10T07:46:50","modified_gmt":"2012-02-10T07:46:50","slug":"how-low-should-your-ldl-go","status":"publish","type":"post","link":"https:\/\/leadershipshape.com\/wardroom\/how-low-should-your-ldl-go\/","title":{"rendered":"How Low Should Your LDL Go?"},"content":{"rendered":"<p style=\"text-align:right;\"><strong><em>by <strong>Carole Jackson<\/strong>, <a href=\"http:\/\/www.bottomlinesecrets.com\/index\/indexes.html?pub=blh\" target=\"_blank\">Bottom Line Health<\/a><\/em><\/strong><\/p>\n<p>&#8220;Keep your LDL cholesterol low&#8221; is practically a medical mantra now. It\u00e2\u0080\u0099s a greater struggle for some folks than for others &#8212; some people are able to achieve a desirable level with little or no effort, while others accomplish it by taking statin drugs. A new tool for lowering LDL emerged about 10 years ago when margarines with plant compounds called <em>phytosterols<\/em> &#8212; known to inhibit absorption of LDL cholesterol in the intestines &#8212; started cropping up in supermarkets. Could these be the ideal solution?<\/p>\n<p><strong>Better than Statins?<\/strong><\/p>\n<p>Phytosterols (as well as <em>phytostanols<\/em>, a subgroup of phytosterols) exist naturally in some vegetable oils, but in amounts too low to affect our cholesterol levels. Once extracted from these oils, however, they become a food additive or supplement that can deliver quite a cholesterol-lowering punch. Indeed, studies showed that consuming about two to three grams of phytosterols a day (you get this from about four to six tablespoons of the margarine) lowers total cholesterol by up to about 10% and LDL by up to about 14%.<\/p>\n<p>Research had examined the effects of ingesting just two to three grams of phytosterols a day&#8230; but what would happen if you doubled or even tripled that intake? It\u00e2\u0080\u0099s known that statin drugs work to only a certain point &#8212; they have what\u00e2\u0080\u0099s known as a &#8220;leveling off&#8221; effect, which means that there is a diminishing effect &#8212; doubling the dose won\u00e2\u0080\u0099t double the result. Does this happen with phytosterols, too?<\/p>\n<p>Recently, a Dutch scientist, Ronald Mensink, MSc, PhD, professor of molecular nutrition in the department of human biology at Maastricht University Medical Centre in The Netherlands, conducted a three-week study to answer that question, using the type of phytosterol called phytostanols.<\/p>\n<p>Ninety-three people with mildly elevated LDL cholesterol were divided into four groups &#8212; consuming no stanols or three, six or nine grams daily. <em>Results:<\/em> The more stanols people ate, the lower their LDL dropped. The three-gram group had a 7.4% decrease on average&#8230; the six-gram group showed an 11.9% decrease&#8230; those consuming nine grams of stanols per day decreased LDL by an average of 17.4%. No adverse effects were found in any of the groups.<\/p>\n<p>But Dr. Mensink urged caution despite the impressive findings &#8212; he said that more research is needed before advising any consumption increase, since we don\u00e2\u0080\u0099t yet have data on the long-term safety of consuming higher levels of sterols.<\/p>\n<p><strong>Dr. Rubman\u00e2\u0080\u0099s Advice<\/strong><\/p>\n<p>When I checked in with <em>Daily Health News<\/em> medical editor Andrew L. Rubman, ND, he agreed that phytosterols &#8212; in the form of supplements or food additives &#8212; may be helpful. Echoing Dr. Mensink\u00e2\u0080\u0099s cautionary note, he said&#8230;<\/p>\n<ul>\n<li>People with high LDL (above 150 mg\/dl) can benefit from phytosterol\/stanol-fortified foods, whether or not they are taking a statin drug.<\/li>\n<\/ul>\n<ul>\n<li>A good phytosterol supplement, such as EP Phytosterols made by Endurance Products (800-483-2532, <a href=\"http:\/\/edhn.bottomlinesecrets.com\/a\/hBMv9b5B74VNIB8VSvTNFNjQQzp\/dhn10\" target=\"_blank\">www.Endur.com<\/a>, $20 for a bottle of 100 tablets, 450 mg each tablet) may be better yet.<\/li>\n<\/ul>\n<ul>\n<li>Until we have further research, consume no more than two to three grams of phytosterols\/stanols per day.<\/li>\n<\/ul>\n<ul>\n<li>Don\u00e2\u0080\u0099t take phytosterol\/stanol supplements or fortified foods if you already have low LDL (below 100 mg\/dl). Yes, they\u00e2\u0080\u0099re natural, said Dr. Rubman, &#8220;but they still have druglike properties that actively interfere with cholesterol uptake, just as some drugs do.&#8221;<\/li>\n<\/ul>\n<p>Dr. Rubman pointed out that having high LDL may not mean your body makes too much &#8212; there are other potential causes as well. It\u00e2\u0080\u0099s therefore important to work with a knowledgeable doctor who can treat the source and not just the symptom.<\/p>\n<blockquote><p>\u00c2\u00a0Source(s):<\/p>\n<p><a href=\"http:\/\/www.nutrim.unimaas.nl\/contentuk\/personal_pages\/M\/0101mensink.html\" target=\"_blank\">Ronald P. Mensink, MSc, PhD<\/a>, professor of molecular nutrition, department of human biology, Maastricht University Medical Centre, The Netherlands.<\/p>\n<p>Andrew L. Rubman, ND, founder and medical director, Southbury Clinic for Traditional Medicines, Southbury, Connecticut. <a href=\"http:\/\/edhn.bottomlinesecrets.com\/a\/hBMv9b5B74VNIB8VSvTNFNjQQzp\/dhn11\" target=\"_blank\">www.SouthburyClinic.com<\/a>.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>by Carole Jackson, Bottom Line Health &#8220;Keep your LDL cholesterol low&#8221; is practically a medical mantra now. It\u00e2\u0080\u0099s a greater struggle for some folks than for others &#8212; some people are able to achieve a desirable level with little or no effort, while others accomplish it by taking statin drugs. A new tool for lowering &hellip; <a href=\"https:\/\/leadershipshape.com\/wardroom\/how-low-should-your-ldl-go\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">How Low Should Your LDL Go?<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"pmpro_default_level":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[],"tags":[],"class_list":["post-1006","post","type-post","status-publish","format-standard","hentry","pmpro-has-access"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p4MGMb-ge","_links":{"self":[{"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/posts\/1006","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/comments?post=1006"}],"version-history":[{"count":0,"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/posts\/1006\/revisions"}],"wp:attachment":[{"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/media?parent=1006"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/categories?post=1006"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/leadershipshape.com\/wardroom\/wp-json\/wp\/v2\/tags?post=1006"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}